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Peer-reviewed articles

1) Feld, N.C., Ekeroth, L.,
Gradel, K.O., Kabell, S., Madsen, M. (2000):
Evaluation of a serological
Salmonella Mix-Elisa for poultry used in a national surveillance programme.
Epidemiology and Infection, 125, 263-268. Abstract.

2) Gradel, K.O., Feld, N.C., Andersen, J.S. (2001):
Serological reactions against
Salmonella in samples from broiler parent stock with and without preceding colibacillosis: a case-control study.
Avian Diseases, 45, 486-491. Abstract.

3) Wedderkopp, A., Gradel, K.O., Jørgensen, J.C., Madsen, M. (2001):
Pre-harvest surveillance of
Campylobacter and Salmonella in broilers in Denmark.
International Journal of Food Microbiology, 68, 53-59. Abstract.

4) Gradel, K.O., Andersen, J.S., Madsen, M. (2002):
Comparisons of sampling procedures and time of sampling for the detection of
Salmonella in Danish infected chicken flocks raised in floor systems.
Acta Veterinaria Scandinavica, 43, 21-30. Article.

5) Gradel, K.O., Rattenborg, E. (2003):
A questionnaire-based, retrospective field study of persistence of
Salmonella Enteritidis and Salmonella Typhimurium in Danish broiler houses.
Preventive Veterinary Medicine, 56, 267-284. Abstract.

6) Gradel, K.O., Corry, J.E.L., Jørgensen, J.C., Andersen, J.S. (2003):
Laboratory heating studies with
Salmonella spp. and Escherichia coli in organic matter, with a view to decontamination of poultry houses.
Journal of Applied Microbiology, 94, 919-928. Abstract.

7) Bang, D.D., Scheutz, F., Gradel, K.O., Nielsen, E.M., Pedersen, K., Engberg, J., Gerner-Schmidt, P., Handberg, K., Madsen, M. (2003):
Detection of seven virulence and toxin genes of
Campylobacter jejuni and Campylobacter coli isolates from different sources and Cytolethal Distending Toxin production suggest potential diversity of pathogenic properties among isolates.
Genome Letters, 2, 62-72. Abstract.

8) Gradel, K.O., Corry, J.E.L., Jørgensen, J.C., Andersen, J.S. (2004):
Monitoring the efficacy of steam and formaldehyde treatment of naturally
Salmonella-infected layer houses.
Journal of Applied Microbiology, 96, 613-622. Abstract.

9) Gradel, K.O., Sayers, A.R., Davies, R.H. (2004):
Surface disinfection tests with
Salmonella and a putative indicator bacterium, mimicking worst-case scenarios in poultry houses.
Poultry Science, 83, 1636-1643. Article.

10) Randall, L.P., Clouting, C.S., Gradel, K.O., Clifton-Hadley, F.A., Davies, R.D., Woodward, M.J. (2005): Farm disinfectants select for cyclohexane resistance, a marker of multiple antibiotic resistance, in Escherichia coli.
Journal of Applied Microbiology, 98, 556-563. Abstract.

11) Gradel, K.O., Randall, L.P., Sayers, A.R., Davies, R.H. (2005):
Possible associations between
Salmonella persistence in poultry houses and resistance to commonly used disinfectants and a putative role of mar.
Veterinary Microbiology, 107, 127-138. Abstract.

12) Gradel, K.O., Schønheyder, H.C., Pedersen, L., Thomsen, R.W., Nørgaard, M., Nielsen, H. (2006): Incidence and prognosis of non-typhoid Salmonella bacteraemia in Denmark: a 10-year county-based follow-up study.
European Journal of Clinical Microbiology & Infectious Diseases, 25, 151-158. Abstract.

13) Nielsen, H., Gradel, K.O., Schønheyder, H.C. (2006):
High incidence of intravascular focus in nontyphoid Salmonella bactaeremia in the age group above 50 years: a population-based study.
APMIS: acta pathologica, microbiologica, et immunologica Scandinavica, 114, 641-645. Abstract.

14) Gradel, K.O., Dethlefsen, C., Schønheyder, H.C., Ejlertsen, T., Sørensen, H.T., Thomsen, R.W., Nielsen, H. (2007):
Severity of infection and seasonal variation of non-typhoid
Salmonella occurrence in humans.
Epidemiology and Infection, 135, 93-99. Abstract.

15) Gradel, K.O., Dethlefsen, C., Schønheyder, H.C., Nielsen, H. (2006):
Magnitude of bacteraemia is associated with increased mortality in non-typhoid salmonellosis: a one-year follow-up study.
APMIS: acta pathologica, microbiologica, et immunologica Scandinavica, 116, 147-153. Article.

16) Gradel, K.O., Dethlefsen, C., Ejlertsen, T., Schønheyder, H.C., Nielsen, H. (2007):
Increased prescription rate of antibiotics prior to non-typhoid
Salmonella infections: a one-year nested case-control study.
Scandinavian Journal of Infectious Diseases, 40, 635-641. Abstract

17) Gradel, K.O., Søgaard, M., Dethlefsen, C., Nielsen, H., Schønheyder, H.C. (2009):
Magnitude of bacteremia as a predictor of mortality during 1 year of follow-up.
Epidemiology and Infection, 137, 94-101. Abstract

18) Gradel, K.O., Schønheyder, H.C., Dethlefsen, C., Kristensen, B., Ejlertsen, T., Nielsen, H. (2008): Morbidity and mortality of elderly patients with zoonotic Salmonella and Campylobacter: a population-based study.
Journal of Infection
, 57, 214-222. Abstract.

19)
Gradel, K.O., Schønheyder, H.C., Kristensen, B., Dethlefsen, C., Ejlertsen, T., Nielsen, H. (2009):
Are host characteristics or exposure factors mainly involved in the acquisition of zoonotic
Campylobacter and Salmonella co-infection in humans?
Foodborne Pathogens and Disease, 6, 251-255. Abstract.

20)
Gradel, K.O., Schønheyder, H.C., Lundbye-Christensen, S., Ejlertsen, T., Nielsen, H. (2009):
Severity of human non-typhoid salmonellosis as a predictor of short and long term mortality.
Scandinavian Journal of Infectious Diseases, 41, 99-104. Abstract.

21) Gradel, K.O., Nørgaard, M., Dethlefsen, C., Schønheyder, H.C., Kristensen, B., Ejlertsen, T., Nielsen, H.
(2009
):
Increased risk of zoonotic
Salmonella and Campylobacter gastroenteritis in patients with haematological malignancies: a population-based study.
Annals of Hematology, 88, 761-767. Abstract.

22)
Gradel, K.O., Nørgaard, M., Schønheyder, H.C., Dethlefsen, C., Ejlertsen, T., Kristensen, B., Nielsen, H. (2010):
Salmonella or Campylobacter gastroenteritis prior to a cancer diagnosis does not aggravate the prognosis: a population-based follow-up study.
APMIS: acta pathologica, microbiologica, et immunologica Scandinavica, 118, 136-142. Abstract.

23) Nielsen, H., Hansen, K.K.,
Gradel, K.O., Kristensen, B., Ejlertsen, T., Østergaard, C., Schønheyder, H.C.
(2010):
Bacteremia as a result of
Campylobacter species: a population-based study of epidemiology and clinical risk factors.
Clinical Microbiology and Infection, 16, 57-61. Abstract.

24)
Gradel, K.O., Nielsen, H.L., Schønheyder, H.C., Ejlertsen, T., Kristensen, B., Nielsen, H. (2009):
Increased short and long term risk of inflammatory bowel disease after
Salmonella or Campylobacter gastroenteritis.
Gastroenterology, 137, 495-501. Abstract.

25) Jensen, U.S., Knudsen, J.D., Østergaard, C., Gradel, K.O., Frimodt-Møller, N., Schønheyder, H.C.
(2010):
Recurrent bacteremia: a 10-year regional population-based study of clinical and microbiological risk factors.
Journal of Infection, 60, 191-199. Abstract.

26) Gradel, K.O., Thomsen, R.W., Lundbye-Christensen, S., Nielsen, H., Schønheyder, H.C. (2011):
Baseline C-reactive protein level as a predictor of mortality in bacteraemia patients: a population-based cohort
study.
Clinical Microbiology and Infection, 17, 627-632. Abstract.

27) Larsen, I.K.,
Gradel, K.O., Helms, M., Hornstrup, M.K., Jürgens, G., Mens, H., Rosager, C.L.,
Clausen, T.H., Kronborg, G., Nielsen, H. (2011):
Non-typhoidal
Salmonella and Campylobacter infections among HIV positive patients in Denmark.
Scandinavian Journal of Infectious Diseases, 43, 3-7. Abstract.

28) Laupland, K.B., Schønheyder, H.C., Andersen, C.Ø., Knudsen, J.D., Valiquette, L., Galbraith, J.,
Kennedy, K.J., Gradel, K.O., for the International Bacteremia Surveillance Collaborative (2011):
Epidemiology of Haemophilus influenza bacteremia: A multi-national population-based assessment.
Journal of Infection, 62, 142-148. Abstract.

29) Andersen, R.M.Ø., Bjørn-Præst, S.O.,
Gradel, K.O., Nielsen, C., Nielsen, H. (2011):
Epidemiology, diagnostic delay and outcome of tuberculosis in North Jutland, Denmark.
Danish Medical Bulletin, 58, A4256. Abstract.
Secondary publication:
Ugeskrift for Læger, 173/12, 901.

30) Janum, S., Søvsø, M.,
Gradel, K.O., Schønheyder, H.C., Nielsen, H. (2011):
C-reactive protein level as a predictor of mortality in liver disease patients with bacteraemia.
Scandinavian Journal of Gastroenterology, 46, 1478-1483. Abstract.

31) Nørgård, B.M., Nielsen, J., Qvist, N.,
Gradel, K.O., de Muckadell, O.B., Kjeldsen, J. (2012):
Pre-operative use of anti-TNF-α agents and the risk of post-operative complications in patients with
ulcerative colitis - a nationwide cohort study.
Alimentary Pharmacology & Therapeutics, 35, 1301-1309. Abstract.

32)
Gradel, K.O., Jensen, T.G., Kolmos, H.J., Pedersen, C., Vinholt, P.J., Lassen, A.T. (2013):
Does C-reactive protein independently predict mortality in adult community acquired bacteraemia patients with known sepsis severity?
APMIS: acta pathologica, microbiologica, et immunologica Scandinavica, 121, 835-842. Abstract.

33)
Gradel, K.O., Knudsen, J.D., Arpi, M., Østergaard, C., Schønheyder, H.C., Søgaard, M., for
the Danish Collaborative Bacteraemia Network (DACOBAN) (2012):
Classification of positive blood cultures: computer algorithms versus physicians' assessment – Development of tools for surveillance of bloodstream infection prognosis using population-based laboratory databases.
BMC Medical Research Methodology, 12, 139. Article.

34) Guldberg, R., Brostrøm, S., Hansen, J.K., Kærlev, L.,
Gradel, K.O., Nørgård, B.M.,
Kesmodel, U.S. (2013):
The Danish Urogynaecological Database – establishment, completeness, and validity.
International Urogynecology Journal, 24, 983-990. Abstract.

35) Guldberg, R., Kesmodel, U.S., Hansen, J.K.,
Gradel, K.O., Brostrøm, S., Kærlev, L.,
Nørgård, B.M. (2013):
Patient reported outcome measures in women undergoing surgery for urinary incontinence and
pelvis organ prolapse in Denmark, 2006-2011.
International Urogynecology Journal, 24, 1127-1134. Abstract.

36) Nørgård, B.M., Nielsen, J., Qvist, N.,
Gradel, K.O., de Muckadell, O.B., Kjeldsen, J. (2013):
Pre-operative use of anti-TNF-α agents and the risk of post-operative complications in patients with Crohn's disease – a nationwide cohort study.
Alimentary Pharmacology & Therapeutics, 37, 214-224. Abstract.

37) Pinholt, M., Østergaard, C., Arpi, M., Bruun, N., Schønheyder, H.C., Gradel, K.O, Søgaard, M.,
Knudsen, J.D. (2013):
Incidence, clinical characteristics and 30-day mortality of enterococcal bacteraemia in Denmark
2006 to 2009: a population-based cohort study.
Clinical Microbiology and Infection, 20, 145-151. Abstract.

38)
Gradel, K.O., Kærlev, L. (2015):
Antibiotic redemptions from the mother's conception to the child's leukaemia diagnosis as compared
to the background population: a nested case-control study.
Pediatric Blood & Cancer, 62, 1155-1161. Abstract.

39) Nielsen, S.L., Pedersen, C., Jensen, T.G.,
Gradel, K.O., Kolmos, H.J., Lassen, A.T. (2014):
Decreasing incidence rates of bacteremia in a Danish region: a 9-year population-based study.
Journal of Infection, 69, 51-59. Abstract.

40) Knudtzen, F.C., Nielsen, S.L.,
Gradel, K.O., Lassen, A.T., Kolmos, H.J., Jensen, T.G.,
Vinholt, P.J., Pedersen, C. (2014):
Characteristics of patients with community-acquired bacteremia who have low levels of
C-reactive protein (
20 mg/L).
Journal of Infection, 68, 149-155. Abstract.

41) Illum, N.O.,
Gradel, K.O. (2014):
The Nordic Five to Fifteen questionnaire could provide the basis for a common neurological
disability variable.
Acta Paediatrica, 103, 879-885. Abstract.

42)
Gradel, K.O., Nielsen, S.L., Pedersen, C., Knudsen, J.D., Østergaard, C., Arpi, M., Jensen, T.G.,
Kolmos, H.J., Schønheyder, H.C., Søgaard, M., Lassen, A.T. (2014):
No specific time window distinguishes between community, healthcare and hospital acquired
bacteremia, but they are prognostically robust.
Infection Control and Hospital Epidemiology, 35, 1474-1482. Abstract.

43)
Gradel, K.O., Schønheyder, H.C., Arpi, M., Knudsen, J.D., Østergaard, C., Søgaard, M. (2014):
The Danish Collaborative Bacteraemia Network (DACOBAN) database.
Clinical Epidemiology, 6, 301-308. Article.

44) Nielsen, S.L., Lassen, A.T.,
Gradel, K.O., Jensen, T.G., Kolmos, H.J., Hallas, J.,
Pedersen, C. (2015):
Bacteremia is associated with excess long-term mortality: a 12-year population-based cohort study.
Journal of Infection, 70, 111-126. Abstract.

45) Nielsen, S.L., Lassen, A.T., Kolmos, H.J., Jensen, T.G.,
Gradel, K.O., Pedersen, C. (2016):
The daily risk of bacteremia during hospitalization and associated 30-day mortality evaluated in
relation to the traditional classification of bacteremia.
American Journal of Infection Control, 44, 167-172. Abstract.

46)
Gradel, K.O., Jensen, U.S., Schønheyder, H.C., Østergaard, C., Knudsen, J.D., Wehberg, S.,
Søgaard, M. (2017):
Impact of appropriate empirical antibiotic treatment on recurrence and mortality in patients with
bacteraemia: a population-based cohort study.
BMC Infectious Diseases, 17, 122. Article.

47) Larsen, M.D., Lose, G., Guldberg, R.,
Gradel, K.O. (2016):
Discrepancies between Patient Reported Outcome Measures when assessing urinary incontinence or
pelvic prolapse surgery.
International Urogynecology Journal, 27, 537-543. Abstract.

48)
Gradel, K.O., Nielsen, S.L., Pedersen, C., Knudsen, J.D., Østergaard, C., Arpi, M., Jensen, T.G.,
Kolmos, H.J., Søgaard, M., Lassen, A.T., Schønheyder, H.C. (2015):
Low completeness of bacteraemia registration in the Danish National Patient Registry.
PLoS One 10(6): e0131682. doi:10.1371/journal.pone.0131682. Article.

49) Magnussen, B.,
Gradel, K.O., Jensen, T.G., Kolmos, H.J., Pedersen, C., Vinholt, P.J., Lassen, A.T.,
(2015):
Association between hypoalbuminaemia and mortality in patients with community-acquired bacteraemia
is primarily related to acute disorders.
PLoS One, 11(9): e0160466. doi:10.1371/journal.pone.0160466. Article.

50) Hansen, M.F., Lose, G., Kesmodel, U.S.,
Gradel, K.O. (2016):
Reoperation for urinary incontinence: A nationwide cohort study, 1998-2007.
American Journal of Obstetrics & Gynecology, 214, 263.e1-e8. Abstract.

51) Illum, N.O.,
Gradel, K.O. (2015):
Creating a disability variable for children with disability using the WHO ICF-CY classification system.
British Journal of Applied Science & Technology, 11, 1-19, Article no. BJAST.19635. Article.

52) Illum, N.O.,
Gradel, K.O. (2015):
Assesing children with disabilities using WHO ICF-CY activity and participation D codes.
Child Neurology Open, October-December 2015, 1-9. DOI: 10.1177/2329048X15613529. Article.

53) Illum, N.O., Bonderup, M., Gradel, K.O. (2016):
Environmental needs in childhood disability analysed by the WHO ICF, Child and Youth Version.
Danish Medical Journal, 63(6), A5238. Article.

54) Hansen, M.F., Lose, G., Kesmodel, U.S., Gradel, K.O. (2016):
Repeat surgery after failed midurethral slings: a nationwide cohort study, 1998-2007.
International Urogynecology Journal, 27, 1013-1019. Abstract.

55)
Gradel, K.O., Nielsen, S.L., Pedersen, C., Knudsen, J.D., Østergaard, C., Arpi, M., Jensen, T.G.,
Kolmos, H.J., Søgaard, M., Lassen, A.T., Schønheyder, H.C. (2016):
Seasonal variation of
Escherichia coli, Staphylococcus aureus, and Streptococcus pneumoniae
bacteraemia according to acquisition and patient characteristics: a population-based study.
Infection Control and Hospital Epidemiology, 37, 946-953. Abstract.

56) Illum, N.O.,
Gradel, K.O. (2015):
Properties of joined WHO ICF-CY body function B codes and activity and participation D codes in
childhood disability.
International Journal of Current Research, 7, 24257-24265. Article.

57) Blixt, T.,
Gradel, K.O., Homann, C., Seidelin, J.B., Schønning, K., Lester, A., Houlind, J.,
Stangerup, M., Gottlieb, M., Knudsen, J.D. (2017):
Asymptomatic carriers contribute to nosocomial
Clostridium difficile infection: a cohort
study of 4508 patients.
Gastroenterology, 152, 1031-1041. Abstract.

58) Thønnings, S., Knudsen, J.D., Schønheyder, H.C., Søgaard, M., Arpi, M.,
Gradel, K.O.,
Østergaard, C. (2016):
Antibiotic treatment and mortality in patients with
Listeria monocytogenes meningitis or bacteraemia.
Clinical Microbiology and Infection, 22, 725-730. Abstract.

59) Hansen, U.D.,
Gradel, K.O., Larsen, M.D. (2016):
Danish Urogynaecological Database.
Clinical Epidemiology, Oct. 25, 8, 709-712. Article.

60) Hansen, S., Nielsen, J., Laursen, R.J., Rasmussen, B.K., Nørgaard, B.M.,
Gradel, K.O.,
Guldberg, R. (2016):
The Danish Neuro-Oncology Registry: establishment, completeness and validity.
BMC Research Notes, 9, 425. Article.

61) Wehberg, S., Guldberg, R.,
Gradel, K.O., Kesmodel, U.S., Munk, L., Andersson, C.B.,
Jølving, L.R., Nielsen, J., Nørgaard, B.M. (2016):
Risk factors and between-hospital variation of caesarean section in Denmark: a cohort study.
Submitted.

62) Illum, N.O.,
Gradel, K.O. (2017):
Parents' assessment of disability in their children using WHO ICF-CY joined body functions and
activity codes related to everyday life.
Clinical Medicine Insights: Pediatrics, 11, 1-11. Article.

63) Hansen, M.F., Lose, G., Kesmodel, U.S.,
Gradel, K.O. (2017):
A national population-based cohort study of urethral injection therapy for female stress and
mixed urinary incontinence – The Danish Urogynaecological Database, 2007-2011.
International Urogynecology Journal, 28, 1309-1317. Abstract.

64) Rasmussen, B.K., Hansen, S., Laursen, R.J., Kosteljanetz, M., Schultz, H., Nørgård, B.M.,
Guldberg, R.,
Gradel, K.O. (2017):
Epidemiology of glioma: clinical characteristics, symptoms, and predictors of glioma patients
grade I-IV in the Danish Neuro-Oncology Registry.
Journal of Neurooncology, in press. Abstract.

65)
Gradel, K.O., Vinholt, P.J., Magnussen, B., Pedersen, C., Jensen, T.G., Kolmos, H.J.,
Lassen, A.T. (2017):
Hypoalbuminemia as a marker of trans-capillary leakage in community-acquired bacteraemia
patients.
Submitted.

66) Kammerlander, H., Nielsen, J., Kjeldsen, J., Knudsen, T.,
Gradel, K.O., Friedman, S.,
Nørgård, B.M. (2017):
Fecal calprotectin during pregnancy in women with inflammatory bowel disease.
Inflammatory Bowel Diseases, accepted for publication.


Book chapter

Gradel, K.O.: Disinfection of empty animal houses - scientific evidence for applied procedures. In Kurladze, G.V. (ed.): Environmental Microbiology Research Trends. New York, USA: Nova Science Publishers, Inc., 2007, pp. 59-98. ISBN 978-1-60021-939-9. Link to the book.



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